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B-type Natriuretic Peptide (BNP)

Published: July 27, 2026Updated: August 25, 2026

BNP is a hormone released by the heart in response to pressure changes, particularly in heart failure. It helps assess cardiac function and diagnose heart failure.

Quick summary

BNP is a diagnostic biomarker for heart failure.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

Units
pg/mL
Clinical utility
diagnostic
Result kind
quantitative
FDA-cleared
Abbott i-STAT BNP Emergency
interpretation: {"text":"0–100 pg/mL: BNP levels within this range are generally considered normal.","label":"Normal"}; {"text":">100 pg/mL: Levels above the reference range may indicate heart failure or other cardiac issues.","label":"Elevated"}

B-type Natriuretic Peptide (BNP) is a hormone produced by the heart ventricles in response to increased wall stress, such as in conditions like heart failure. It plays a crucial role in regulating blood pressure, fluid balance, and cardiac function.

Measuring BNP levels in the blood is a valuable diagnostic tool for identifying and assessing the severity of heart failure. Elevated levels typically indicate cardiac dysfunction and can help guide treatment strategies.

The reference range for BNP is generally between 0–100 pg/mL. Levels above this range may suggest heart failure or other cardiovascular conditions, prompting further clinical evaluation.

Frequently asked questions

What does a high BNP level mean?
A high BNP level typically indicates increased stress on the heart, often due to heart failure or other cardiac conditions.
Can BNP levels change over time?
Yes, BNP levels can fluctuate based on the patient's condition, treatment, and overall cardiac health.
  1. 1
    BNP Testing in Heart FailureSource
  2. 2
    Understanding BNP and NT-proBNPSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy